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. 2022 Jun 7;13:911097. doi: 10.3389/fphys.2022.911097

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Copyright © 2022 Briggs, Hambly, Simão-Gurge, Garrison, Khaku, Van Susteren, Lewis, Riffell and Luckhart.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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P. yoelii yoelii 17XNL oocyst infection in A. stephensi following priming for 3 days with 5-HT or water (control) soaked cotton balls. (A) Numbers of infected and uninfected mosquitoes by treatment with significant differences noted among pairs, and (B) data from (A) shown as percentages of uninfected and infected mosquitoes in each group. N = 6; Fisher’s exact test (α = 0.05), **control vs. 1.5 μM p = 0.0021. (C) Mean P. y. yoelii 17XNL midgut oocysts. N = 6; 1-way ANOVA (α = 0.05), p = 0.0410, *control vs. 0.15 µM, p = 0.0178, *control vs. 1.5 µM, p = 0.0490.