Table 2.

Effect of elevated IL-6 and IL-10 levels on disease severity and mortality in COVID-19 patients.

Interleukin	Covariates	Test of association			Test of heterogeneity			Publication bias (P-value)
		Mean difference	95% CI	P-value	Model	P-value	I2 (%)	Egger’s test	Begg-Mazumdar’s test
IL-6	Severity	19.98	17.56, 22.40	<.001	Random	<.001	97	0.005	0.023
	Mortality	42.11	36.86, 47.36	<.001	Random	<.001	98	0.718	0.716
IL-10	Severity	1.35	0.90, 1.80	<.001	Random	<.001	91	0.091	0.455
	Mortality	4.79	2.83, 6.75	<.001	Random	<.001	81	0.669	1.00