Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 21;13:267. doi: 10.1186/s13287-022-02916-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 3 — The body weight, litter size, organ coefficient and distribution in POF mice after CD146 +/− MSCs treatment. A The time scale of animal experiment was marked. The stem cells were injected on days 7 and 14 after modeling, and the mouse mating experiment was conducted on day 14, the mice were killed for the first time in 21 days and for the second time in 35 days. B The body weight changes of mice. C The litter size of mice. D, E Ovaries and spleens coefficient at two weeks (2 W)and four weeks (4 W)after the first stem cell injection. F, G In vivo imaging of CD146 +/− MSCs at days 0, 3, and 6 after intravenous tail vein injection. As can be observed in the images and from the radiancestatistics, CD146 + MSCs lived longer and more in the lungs than CD146 - MSCs