Table 3.

DOs and DON'Ts in screening and chemoprevention of BO and OAC

Screening

DOs

Screen patients with multiple risk factors for OAC

Investigate the family history of patients with GORD as a means to identify those at higher risk for BO or OAC

Consider the use of alternative screening technologies such as Cytosponge or transnasal endoscopy depending on local availability

DON'Ts

Endoscope all patients with gastro-oesophageal reflux symptoms

Chemoprevention

DOs

Consider aspirin in the presence of BO and other cardiovascular risk factors

Consider low-dose PPI as chemoprevention in patients with BO regardless of symptoms

DON'Ts

Use high-dose PPI as routine strategy to reduce the cancer risk in BO

Use aspirin in all patients with BO