Table 1.
Patients’ characteristics and items of the RESP, PRESERVE, and Roch Scores according to ECMO decision
| Overall, N = 535a | ECMO decision, N = 302a | Non ECMO decision, N = 233a | p valueb | |
|---|---|---|---|---|
| Age (years) | 55 (47–61) | 52 (44–58) | 59 (51–64) | < 0.001 |
| 18–49 | 171 (32) | 123 (41) | 48 (21) | |
| 50–59 | 208 (39) | 134 (44) | 74 (32) | |
| ≥ 60 | 156 (29) | 45 (15) | 111 (48) | |
| Immunocompromised status | 42 (8) | 18 (6) | 24 (10) | 0.064 |
| Body mass index > 30 kg/m2 | 260 (50) | 143 (48) | 117 (52) | 0.38 |
| Viral pneumonia | 535 (100) | 302 (100) | 233 (100) | |
| Central nervous system dysfunction | 0 (0) | 0 (0) | 0 (0) | |
| Acute associated (non pulmonary) infection | 0 (0) | 0 (0) | 0 (0) | |
| Cardiac arrest before ECMO | 5 (1) | 1 (0.3) | 4 (2) | 0.17 |
| Mechanical ventilation before decision | < 0.001 | |||
| < 48 h | 6 (1) | 2 (1) | 4 (2) | |
| 48 h–7 days | 332 (65) | 229 (80) | 103 (46) | |
| > 7 days | 172 (34) | 56 (20) | 116 (52) | |
| Plateau pressure before decision > 30 cmH2O | 198 (41) | 111 (44) | 87 (38) | 0.20 |
| PEEP before decision < 10 cmH2O | 80 (16) | 43 (16) | 37 (16) | 0.84 |
| Prone positioning before decision | 498 (95) | 284 (94) | 214 (96) | 0.22 |
| Neuro-muscular blockade agents before decision | 512 (96) | 291 (96) | 221 (95) | 0.39 |
| Bicarbonate infusion before decision | 0 (0) | 0 (0) | 0 (0) | – |
| PaCO2 > 75 mmHg | 62 (12) | 35 (12) | 27 (12) | 0.88 |
| RESP score | 2 (1–4) | 3 (2–5) | 2 (1–3) | < 0.001 |
| Preserve score | 3 (1–4) | 2 (0–4) | 3 (1–4) | 0.029 |
| Roch score | 3 (2–4) | 3 (3–4) | 3 (2–4) | 0.89 |
| SOFA score | 12 (9–14) | 12 (9–14) | 12 (9–14) | 0.31 |
| > 12 | 215 (40) | 120 (40) | 95 (41) | 0.81 |
ECMO extracorporeal membrane oxygenation, RESP Respiratory ECMO Survival Prediction score, PRESERVE PRedicting dEath for SEvere ARDS on VV-ECMO, PEEP positive end-expiratory pressure, SOFA Sequential Organ Failure
an (%); Median (IQR)
bPearson's Chi-squared test; Fisher's exact test; Wilcoxon rank sum test