TABLE 1.

Demographic and laboratory information for patients with CML in blast phase, Johannesburg, South Africa, 08 April 2016 to 16 October 2019.

Parameter	All patients (n = 22)	Deceased patients (n = 16)	Patients in remission (n = 5)
Male to female ratio	1.2:1	1.3:1	1.5:1
Age (years)
Median	34	32	37
IQR	21	15	25
HIV positive
N	5†	4‡	1§
%	50.0	36.0	33
Haemoglobin (g/dL)
Median	7.6	7.1	7.6
IQR	3.4	4.2	0.3
Platelet count ( × 109/L)
Median	79	31	101
IQR	180	177	324
White cell count ( × 109/L)
Median	58.5	37.3	144.2
IQR	282.9	175.4	367.4
Neutrophils ( × 109/L)
Median	7.66	7.3	72.2
IQR	56.2	39.8	91.8
Basophils (%)
Median	4.5	2. 5	5.4
IQR	11	10.5	7
Peripheral blast count ( % )
Median	38.5¶	56	18
IQR	47	41	26
Immunophenotype
Myeloid,
N	14	9	4
%	63.6	56.3	80.0
Lymphoid
N	6	5	1
%	27.3	31.2	20.0
Ambiguous
N	2	2	-
%	9.1	12.5	-

Note: HIV testing was not routinely performed resulting in a the lower number of individuals with HIV results.

CML, chronic myeloid leukemia; IQR, interquartile range.

^†, N = 10 (No HIV results available for 12 patients);

^‡, N = 7; (No HIV results available for 9 patients);

^§, N = 3 (No HIV results available for 2 patients);

^¶, N =21 (1 not reported).