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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: J Allergy Clin Immunol Pract. 2022 Mar 10;10(6):1598–1605.e2. doi: 10.1016/j.jaip.2022.02.037

FIGURE 2.

FIGURE 2.

Histological features (hematoxylin and eosin) of gastric biopsies at baseline and week 24 at 200×. (A) Subject 16 at baseline with increased eosinophils in the lamina propria and glandular epithelium, and epithelial changes with marked (>5 HPF) increased nuclear:cytoplasmic ratio. (B) Subject 16 at week 24 with persistent epithelial changes consisting of marked (>5 HPF) increased nuclear:cytoplasmic ratio and reduced mucin despite resolution of tissue eosinophils. (C) Subject 16 at 1 year with persistent epithelial changes. (D) Subject 14 at baseline with increased eosinophils in the lamina propria and glandular epithelium, and mild/moderate epithelial changes (≤5 HPF) consisting of reduced mucin and increased nuclear:cytoplasmic ratio. (E) Subject 14 at week 24 with persistent epithelial changes with reduced mucin and increased nuclear:cytoplasmic ratio found in more than 5 HPF despite resolution of tissue eosinophils. Black arrows, eosinophils; blue arrows, areas of increased nuclear:cytoplasmic ratio and reduced mucin; inset (black box, 400×).