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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: J Allergy Clin Immunol Pract. 2022 Mar 10;10(6):1598–1605.e2. doi: 10.1016/j.jaip.2022.02.037

TABLE II.

Benralizumab allowed some subjects to reduce medical therapies for EGID and liberalize dietary restrictions

No. BL Tx Diet at BL Week 48 Tx Diet at week 48
6* P 10 mg daily, HU 1 g daily Unrestricted P 15 mg Unrestricted
7 Budesonide 9 mg FV 440 twice a day Avoids: chicken and beef plus FA foods Budesonide 6 mg, FV 440 twice a day No attempt to reintroduce foods; eats more freely
11 Budesonide 3 mg Unrestricted None Unrestricted
13 None Avoids: carrots, peas, apple, mango, banana, watermelon, kiwi, strawberry, turkey, direct egg, corn, wheat, oats None Reintroduced most foods
Avoids: wheat and mango
14 FV 220 2p twice a day Consumes only shrimp, potato, fruit (apple, pear, lemon, banana), vegetables (broccoli, lettuce) FV 220 2p twice a day Reintroduced fish, poultry, tomato, carrots.
Unable to tolerate avocado and shrimp
15* None Unrestricted, but planned mealtimes to avoid symptoms None Eats unrestricted diet freely
16 FV 220 2p twice a day Avoids: corn, rice, most meats, shrimp, shellfish, and pure egg FV 220 2p twice a day No attempts to reintroduce foods

Budesonide, Budesonide slurry; P, prednisone; FA, food allergy; FV, swallowed fluticasone; HU, hydroxyurea; Tx, treatment.

*

Subjects with lymphoid HES and GI involvement. Remaining subjects were HES single-organ overlap (EGID). Subject #6 relapsed at week 32 and taken off benralizumab.