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. 2021 Jul 30;12(6):1282–1296. doi: 10.1177/21925682211034500

Table 2.

Risk of Bias Measured Using the ROBINS-I Tool.

Bias due to confounding Bias in selection of participants Bias in classifications of interventions Bias due to deviations from intended interventions Bias due to missing outcome data Bias in measurement of the outcome Bias in selection of the reported results Overall risk of bias
Alluri et al 2020 28 graphic file with name 10.1177_21925682211034500-img2.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img5.jpg graphic file with name 10.1177_21925682211034500-img5.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg
Buell et al 2018 29 graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img5.jpg graphic file with name 10.1177_21925682211034500-img5.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img3.jpg
Buell et al 2019 30 graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img2.jpg graphic file with name 10.1177_21925682211034500-img2.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img2.jpg
Ghobrial et al 2017 35 graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img5.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg
Han et al 2019 36 graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img5.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg
Hart et al 2008 37 graphic file with name 10.1177_21925682211034500-img2.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img5.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img2.jpg
Hassanzadeh et al 2013 41 graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg
Iyer et al 31 graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img5.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img2.jpg
Lee et al 2019 43 graphic file with name 10.1177_21925682211034500-img2.jpg graphic file with name 10.1177_21925682211034500-img2.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img2.jpg
Line et al 2020 32 graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img2.jpg graphic file with name 10.1177_21925682211034500-img2.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img2.jpg
Matsumura et al 2018 42 graphic file with name 10.1177_21925682211034500-img2.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img5.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img2.jpg
Martin et al 2013 38 graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img3.jpg
Raman et al 2017 39 graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img3.jpg
Rodriguez-Fontan et al 2019 34 graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img2.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img2.jpg
Safaee et al 2018 33 graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img2.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img5.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img2.jpg
Sandquist et al 2015 44 graphic file with name 10.1177_21925682211034500-img2.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img5.jpg ? graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img2.jpg
Theologis and Burch 2015 40 graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img2.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img5.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img2.jpg
Viswanathan et al 2018 45 graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img4.jpg graphic file with name 10.1177_21925682211034500-img3.jpg
Overall risk of bias criteria:
Low: low in all domains
Moderate: low or moderate in all domains
Severe: severe in ≥ 1 domain
Critical: critical in ≥ 1 domain