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. 2022 Jun 14;10(7):e978–e988. doi: 10.1016/S2214-109X(22)00119-X

Table 2.

Crude and fully adjusted incidence rates of laboratory-confirmed Salmonella yphi and Salmonella Paratyphi A and incidence of hospitalisation per 100 000 person-years, by age group

Incidence of enteric fever
Incidence of hospitalisation due to enteric fever

Salmonella Typhi
Salmonella Paratyphi A
Salmonella Typhi
Salmonella Paratyphi A
Crude incidence per 100 000 person-years Fully adjusted incidence per 100 000 person-years Crude incidence per 100 000 person-years Fully adjusted incidence per 100 000 person-years Crude incidence per 100 000 person-years Fully adjusted incidence per 100 000 person-years Crude incidence per 100 000 person-years Fully adjusted incidence per 100 000 person-years
Bangladesh: Dhaka Shishu Hospital and Shishu Shasthya Foundation Hospital
<2 years 160 (133–191) 780 (638–968) 22 (13–35) 81 (66–101) 59 (43–79) 374 (300–507) 4 (1–11) 38 (30–51)
2–4 years 217 (195–239) 1491 (1244–1804) 31 (23–41) 188 (157–228) 69 (57–82) 557 (448–755) 8 (4–13) 69 (56–94)
5–15 years 93 (86–101) 1302 (1038–1642) 15 (12–19) 208 (165–262) 24 (20–28) 200 (161–271) 3 (2–5) 30 (24–41)
Overall 103 (97–109) 913 (765–1095) 16 (13–18) 128 (107–154) 30 (27–33) 242 (195–328) 3 (2–5) 33 (26–44)
Nepal: Dhulikhel Hospital
<2 years 37 (1–311) 156 (100–259) NA* NA* NA* NA* NA* NA*
2–4 years 19 (1–164) 159 (102–262) 10 (0–109) NA* 10 (0–109) 53 (36–151) NA* NA*
5–15 years 60 (28–116) 570 (310–1124) 9 (0–38) 114 (62–224) 31 (11–79) 123 (85–348) 2 (0–25) 25 (17–70)
16–25 years 67 (36–123) 406 (219–820) 17 (4–51) 117 (65–233) 13 (1–42) 103 (70–290) 2 (0–22) 32 (22–92)
>25 years 18 (9–36) 172 (119–256) 3 (0–12) 9 (6–14) 4 (1–15) 38 (26–106) NA* NA*
Overall 36 (24–51) 268 (202–362) 7 (3–16) 46 (34–62) 10 (5–20) 67 (46–189) 1 (0–7) 12 (8–34)
Nepal: Kathmandu Medical College
<2 years 8 (0–71) 251 (120–613) 9 (0–71) NA* 8 (0–71) 178 (48–850) NA* NA*
2–4 years 28 (8–72) 227 (102–522) 9 (0–39) 227 (103–521) 12 (2–51) 140 (38–672) NA* NA*
5–15 years 46 (31–65) 423 (228–826) 7 (2–15) 66 (35–153) 16 (8–29) 398 (107–1890) 1 (0–8) 60 (16–287)
16–25 years 68 (53–84) 653 (313–1440) 12 (7–20) 169 (79–381) 19 (11–28) 504 (135–2394) 2 (0–6) 131 (35–624)
>25 years 11 (7–16) 130 (76–230) 3 (1–6) 34 (20–61) 2 (1–5) 96 (26–458) 1 (0–3) 25 (7–120)
Overall 31 (26–37) 330 (230–480) 6 (4–9) 81 (56–118) 9 (6–12) 249 (67–1191) 1 (0–3) 61 (16–291)
Pakistan: Aga Khan University Hospital
<2 years 43 (24–74) 282 (191–449) 1 (0–12) 10 (6–18) 20 (7–41) 138 (102–208) 1 (0–12) 4 (3–6)
2–4 years 36 (23–54) 371 (265–534) 4 (0–10) 38 (26–56) 19 (10–32) 116 (86–175) 1 (0–8) 9 (7–14)
5–15 years 25 (19–32) 280 (201–397) 3 (2–7) 42 (30–60) 11 (7–16) 71 (52–107) 1 (0–3) 9 (7–14)
16–25 years 11 (7–17) 152 (103–230) 4 (2–8) 60 (41–92) 5 (2–9) 36 (26–54) 1 (0–2) 14 (10–21)
>25 years 3 (2–5) 22 (18–28) 2 (1–3) 10 (8–13) 1 (0–2) 10 (8–16) 0 (0–1) 4 (3–6)
Overall 12 (10–14) 103 (85–126) 3 (2–4) 23 (19–29) 6 (4–7) 38 (28–57) 1 (0–1) 8 (6–11)
Pakistan: Kharadar General Hospital
<2 years 175 (122–244) 628 (470–889) 4 (0–28) 8 (6–12) 40 (17–79) 422 (307–708) NA* NA*
2–4 years 146 (113–185) 901 (662–1269) 1 (0–8) 6 (4–8) 36 (22–59) 394 (287–664) NA* NA*
5–15 years 29 (21–38) 344 (249–483) 0 (0–2) NA* 5 (2–10) 88 (64–147) NA* NA*
16–25 years 3 (1–8) 36 (24–57) NA* NA* 1 (0–4) 10 (8–18) NA* NA*
>25 years 1 (0–3) 8 (6–10) NA* NA* 0 (0–2) 3 (2–5) NA* NA*
Overall 24 (21–28) 176 (144–216) 0 (0–1) 1 (1–1) 5 (3–7) 64 (46–107) NA* NA*

Crude incidence includes patients from within the catchment area recruited from outpatient departments, inpatient departments, surgical wards, hospital laboratories, and laboratory network sites. Fully adjusted incidence includes patients from within the catchment area recruited from outpatient departments, inpatient departments, and surgical wards only. NA=not applicable.

*

No observed cases and therefore insufficient data to estimate incidence.