Table 2.

Positive associations between rCMglc and semantic fluency in overall group (N= 416)

Index	Brain Regions	BA	Coordinates (mm)			Extent Voxels (N)	T value	Z score	p (uncorrected)
			X	Y	Z
Total Score	Bilateral caudate, angular gyrus, PCC, precuneus	–/39/23/7	10	12	6	1598890	5.82	5.70	< 0.001
	L middle frontal gyrus	8	−26	28	40	24627	4.71	4.65	< 0.001
	R middle frontal gyrus	8	24	32	40	25010	4.48	4.43	< 0.001
	L insula	13	−39	14	3	3553	4.07	4.02	< 0.001
	L transverse temporal gyrus	41	−45	−24	14	2204	3.86	3.82	< 0.001
	L anterior cingulate	32	−5	42	11	3029	3.42	3.40	< 0.001
	R insula	13	39	16	5	1826	3.41	3.38	< 0.001
Mean cluster size	No regions
Switching	Bilateral caudate, L thalamus	–	−11	15	5	15940	5.06	4.98	< 0.001
	L inferior parietal lobule	40	−37	−51	22	7144	4.44	4.39	< 0.001
	R middle frontal gyrus	8	23	30	40	1209	3.76	3.73	< 0.001
	L cingulate gyrus	31	−1	−42	32	1932	3.62	3.59	< 0.001
	R supramarginal gyrus, angular gyrus	40/39	46	−43	33	2224	3.55	3.52	< 0.001
	L insula	13	−40	14	3	1753	3.55	3.52	< 0.001
	L middle frontal gyrus	8	−22	27	36	1286	3.51	3.48	< 0.001
	L middle temporal gyrus	20	−56	−37	−9	1281	3.44	3.41	< 0.001
Hard switching	No regions
Cluster switching	R caudate	–	12	15	5	2563	4.25	4.20	< 0.001
	L caudate		−12	7	13	2408	4.08	4.04	< 0.001

SPM12 analysis of covariance output for all patients with age, education, and sex as covariates; BA, Brodmann areas; L, left hemisphere; R, right hemisphere; PCC, posterior cingulate cortex.