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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: J Alzheimers Dis. 2022;85(4):1689–1700. doi: 10.3233/JAD-215292

Table 5.

Positive associations between rCMglc and semantic fluency in aMCI (amnestic MCI) group (N= 179)

Index Brain Regions BA Coordinates (mm)
Extent Voxels (N) T value Z score p (uncorrected)
X Y Z
Total Score L middle frontal gyrus 10 −23 56 21 1079 4.07 3.97 < 0.001
R superior frontal gyrus 10 26 52 24 592 4.03 3.94 < 0.001
R anterior insula 13 38 10 −8 1722 3.90 3.81 < 0.001
L anterior cingulate 32 −1 40 9 1078 3.74 3.67 < 0.001
L caudate −5 15 −2 1103 3.55 3.48 < 0.001
L thalamus −7 −7 11 402 3.54 3.47 < 0.001
R middle temporal gyrus 21 65 −19 −6 262 3.41 3.35 < 0.001
R inferior temporal gyrus 20 59 −32 −21 612 3.40 3.34 < 0.001
L inferior temporal gyrus 20 −48 −5 −34 151 3.34 3.29 < 0.001
Switching R superior temporal gyrus 38 41 3 −12 1392 3.96 3.87 < 0.001
R inferior temporal gyrus 20 45 −16 −27 106 3.33 3.28 < 0.001
L superior frontal gyrus 10 −19 57 14 76 3.28 3.22 < 0.001
R superior frontal gyrus 10 26 54 22 24 3.22 3.17 < 0.001
Cluster switching L thalamus −11 −8 13 673 3.73 3.66 < 0.001
L caudate −10 18 0 244 3.45 3.38 < 0.001
R Thalamus 3 −7 −3 112 3.36 3.30 < 0.001
R caudate 10 16 0 193 3.34 3.28 < 0.001
R inferior parietal lobule 40 62 −28 38 149 3.33 3.27 < 0.001

SPM12 analysis of covariance output for all patients with age, education, and sex as covariates; BA, Brodmann areas; L, left hemisphere; R, right hemisphere; PCC, posterior cingulate cortex.