TABLE 2.

Follow-Up Changes of Clinical Scales and Phosphorylated α-Synuclein Load in Curcumin-Supplemented and Untreated Parkinson Disease Patients

	Supplemented	p-Value	Untreated	p-Value
UPDRS off (score)	5 ± 5	0.0016*	11 ± 5	0.0001*
H&Y (score)	0.2 ± 0.4	0.0655	0.7 ± 0.4	0.0001*
COMPASS-31 (score)	−0.5 ± 3	0.99	6 ± 4	0.11
NMSS (score)	−2 ± 0.6	0.49	8 ± 7	0.0001*
Samples rate (%)	−9 ± 8	0.52	18 ± 15	0.1
Adnexa rate (%)	−5 ± 3	0.6	4 ± 8	0.93
L-dopa (mg/day)	0	–	150 ± 120	0.59

p-Values refer to comparisons from baseline (Table 1) and follow-up measurements. Data are reported as mean±SE.

^*Significant differences.