Table 2.

Logistic and linear regression analyses for the relationship of physical activity with AD biomarkers

Dependent variable	Independent variable	OR	95% CI	p
Aβ positivity	Midlife PA	1.002	0.999~1.006	0.226
	Late-life PA	1.002	0.998~1.006	0.292
Dependent variable	Independent variable	Beta	95% CI	p
Aβ retention	Midlife PA	0.046	0.000~0.001	0.386
	Late-life PA	0.012	0.000~0.001	0.819
AD-CM	Midlife PA	0.028	0.000~0.000	0.649
	Late-life PA	0.048	0.000~0.000	0.427
AD-CT	Midlife PA	−0.007	0.000~0.000	0.889
	Late-life PA	0.075	0.000~0.000	0.145

Adjusted for age, sex, education, apolipoprotein E ε4, vascular risk score, cognitive activity score, and clinical diagnosis. AD, Alzheimer’s disease; OR, odds ratio; CI, confidence interval; Aβ, amyloid-β; PA, physical activity; AD-CM, Alzheimer’s disease signature region cerebral glucose metabolism; AD-CT, Alzheimer’s disease signature cortical thickness.