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A. Study Design. A schematic of the study design showing the concept of genetically regulated expression (GReX) and applied to three PTSD symptom cluster. B-D. Three-tiered Manhattan plots of three PTSD symptoms B-Avoidance, C-Hyperarousal, D-Reexperiencing, the lowest layer is TWAS, middle is SPWAS, and top is PWAS (See text for more details). E. The Venn diagram of overlapping genes across the three PTSD symptom clusters.
