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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Nat Rev Genet. 2021 Jul 1;22(11):712–729. doi: 10.1038/s41576-021-00377-1

Figure 1 |. From epidemiology and gene discovery to biology of substance use disorders.

Figure 1 |

Genome-wide association datasets can be used as the basis for multiple analytical approaches to disentangle the biology of the traits investigated (e.g., cellular processes and molecular functions) and to understand the mechanisms underlying the associations observed in epidemiological studies.