Table 1. Clinical and demographic information of the 10 patients with hypoxemic breakthrough COVID-19 infection and auto-Abs neutralizing type I IFNs.

HTN: hypertension, AF: atrial fibrillation. APS-1: auto-immune polyendocrine syndrome type 1.

Patient	Origin	Residence	Sex	Age	Comorbidities	Vaccine source	Doses number	Time of disease post vaccination (weeks)	ICU	Classification	Outcome
P1	American	USA	M	80	Diabetes, asthma	Pfizer	2	2	Yes	Critical	Alive
P2	Greek	Greece	F	82	HTN, myasthenia gravis, hashimoto, dyslipidemia	Pfizer	2	4	Yes	Critical	Alive
P3	Greek	Greece	M	73	HTN, diabetes, dyslipidemia, glaucome	Pfizer	2	2	Yes	Critical	Alive
P4	Greek	Greece	M	86	HTN, diabetes, dyslipidemai, AF, benign prostate hyperplasia, parkinson	Pfizer	2	12	Yes	Critical	Alive
P5	Greek	Greece	M	73	Diabetes, coronary heart disease	Pfizer	2	3	No	Severe	Alive
P6	Greek	Greece	F	77	HTN, diabetes, dyslipidemia	Pfizer	2	16	No	Severe	Alive
P7	Cambodian	France	M	71	HTN	Pfizer	2	15	Yes	Critical	Alive
P8	French	France	F	86	NA	Pfizer	2	6	No	Critical	Alive
P9	American	USA	M	80	NA	Pfizer	2	2	No	Critical	Alive
P10	French	France	M	43	APS-1	Pfizer	2	2	No	Severe	Alive