Table 2.
Change in KCCQ-CS [β (95% CI)] | P | All-cause readmission [OR (95% CI)] | P | Days rehospitalized [IRR (95% CI)] | P | |
---|---|---|---|---|---|---|
Unadjusted analysis | ||||||
Insufficient calorie intake | −11.7 (−25.2 – 1.84) | 0.09 | 4.5 (1.3–15.2) | 0.02 | 4.6 (1.4–15.9) | 0.02 |
Adjusted analyses | ||||||
Insufficient calorie intake | −14.6 (−27.3 -- −1.9) | 0.03 | 14.5 (2.2–94.4) | 0.005 | 31.3 (4.3–229.3) | 0.001 |
Age (years) | −0.6 (−1.5 – 0.2) | 0.17 | ||||
Sex (female) | −8.2 (−21.4 – 5.1) | 0.22 | ||||
Discharge KCCQ-CS (per point) | −0.5 (−0.8 -- −0.2) | 0.001 | 0.96 (0.9–1.0) | 0.09 | ||
Randomization assignment | 4.3 (−8.2 – 16.7) | 0.50 | 3.2 (0.6–16.8) | 0.17 | ||
OPTIMIZE-HF risk score (per point) | 1.2 (1.0–1.4) | 0.02 | 1.1 (0.99–1.3) | 0.08 | ||
Cardiovascular admissions in 12 mos. | reference | |||||
(0, reference) | ||||||
1 | 2.6 (0.1–53.8) | 0.53 | ||||
2 or more | 1.7 (0.1–24.1) | 0.70 | ||||
Nutritional Risk Index (not at risk, reference) | reference | reference | ||||
Mild risk | 25.2 (2.5–253.6) | 0.006 | 6.7 (0.9–47.4) | 0.06 | ||
Moderate risk | 7.7 (1.3–45.9) | 0.02 | 2.5 (0.6–11.4) | 0.23 |
Abbreviations: KCCQ-CS, Kansas City Cardiomyopathy Questionnaire Clinical Summary; OPTIMIZE-HF, Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure