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. Author manuscript; available in PMC: 2022 Jun 21.
Published in final edited form as: JACC Heart Fail. 2020 Jul 8;8(9):756–764. doi: 10.1016/j.jchf.2020.04.004

Table 2.

Unadjusted and adjusted analyses for clinical outcomes

Change in KCCQ-CS [β (95% CI)] P All-cause readmission [OR (95% CI)] P Days rehospitalized [IRR (95% CI)] P
Unadjusted analysis
Insufficient calorie intake −11.7 (−25.2 – 1.84) 0.09 4.5 (1.3–15.2) 0.02 4.6 (1.4–15.9) 0.02
Adjusted analyses
Insufficient calorie intake −14.6 (−27.3 -- −1.9) 0.03 14.5 (2.2–94.4) 0.005 31.3 (4.3–229.3) 0.001
Age (years) −0.6 (−1.5 – 0.2) 0.17
Sex (female) −8.2 (−21.4 – 5.1) 0.22
Discharge KCCQ-CS (per point) −0.5 (−0.8 -- −0.2) 0.001 0.96 (0.9–1.0) 0.09
Randomization assignment 4.3 (−8.2 – 16.7) 0.50 3.2 (0.6–16.8) 0.17
OPTIMIZE-HF risk score (per point) 1.2 (1.0–1.4) 0.02 1.1 (0.99–1.3) 0.08
Cardiovascular admissions in 12 mos. reference
(0, reference)
1 2.6 (0.1–53.8) 0.53
2 or more 1.7 (0.1–24.1) 0.70
Nutritional Risk Index (not at risk, reference) reference reference
Mild risk 25.2 (2.5–253.6) 0.006 6.7 (0.9–47.4) 0.06
Moderate risk 7.7 (1.3–45.9) 0.02 2.5 (0.6–11.4) 0.23

Abbreviations: KCCQ-CS, Kansas City Cardiomyopathy Questionnaire Clinical Summary; OPTIMIZE-HF, Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure