Table 3.
Biochemical quantification of brain tissue biomolecules.
| Group | MAO (pg/mL) | MDA (U/mg) | SOD (U/mg) | |
|---|---|---|---|---|
| p = 0.0737 | p = 0.0001 | p < 0.0001 | ||
| F = 2.447 | F = 9.561 | F = 11.60 | ||
| CTR | 180.3 ± 32.57 |
0.460 ± 0.03 |
107.6 ± 3.63 |
|
| GLD | 122.0 ± 1.36 |
0.439 ± 0.09d |
121.9 ± 8.07d |
|
| STZ | 136.8 ± 10.07 |
0.903 ± 0.04*** |
50.74 ± 5.23** |
|
| STZ+GLD (2WK) | 135.8 ± 9.87 |
0.469 ± 0.09c |
125.0 ± 5.98c |
|
| STD+GLD (4WK) | 117.1 ± 8.38 |
0.566 ± 0.03c |
111.0 ± 11.74c |
CTR = control; GLD = gliclazide; STZ = streptozotocin; MAO = monoamine oxidase; MDA = malondialdehyde; SOD = superoxide dismutase.
*** = Significantly different from control at p < 0.001; ** = Significantly different from control at p < 0.01; c = Significantly different from STZ group at p < 0.05