Table 3.
Characteristics of dendritic spines in the frontal cortex regions of the dams of VEH: Vehicle, DFx: Desferrioxamine, and Iron (Fe 0.005, 0.8, 8 mgkg−1) treatment group.
| Treatment mg/kg (n = sample size) | |||||
|---|---|---|---|---|---|
| Spine Characteristics | VEH (n = 400) | DFx-50 (n = 320) | Fe 0.0005 (n = 400) | Fe 0.8 (n = 360) | Fe 8.0 (n = 470) |
| Mushroom (width > 0.6 µm) | 300 (75%) | 190 (59.38%) | 250 (62.5%) | 260 (72.22%) | 280 (59.57%) |
| Filopodia (length > 2 µm) | 10 (2.5%) | 5 (1.56) | 30 (7.5%) | 20 (5.56%) | 10 (2.13%) |
| Stubby (LWR < 1 µm) | 5 (1.25%) | 0 (0%) | 10 (2.5%) | 10 (2.78%) | 30 (6.39%) |
| Long thin (length < 1 µm) | 10 (2.5%) | 10 (3.12%) | 40 (10%) | 10 (2.78%) | 90 (19.17%) |
| Thin (length < 2 µm) | 50 (12.5%) | 60 (18.72%) | 70 (17.5%) | 20 (5.56%) | 150 (31.95%) |
| Branches (2 or more) | 5 (1.25%) | 55 (17.16%) | 40 (10%) | 40 (11.12%) | 10 (2.13%) |