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. 2022 Apr 20;12:280–296. doi: 10.1016/j.ibneur.2022.04.004

Table 4.

Characteristics of dendritic spines in the frontal cortex regions of the dams of VEH: Vehicle, DFx: Desferrioxamine, and Fluoxetine (Flx 3, 10, 30 mgkg−1) treatment group.

Treatment mg/kg (n = sample size)
Spine Characteristics VEH (n = 400) DFx-50 (n = 320) Flx 3 (n = 300) Flx 10 (n = 330) Flx 30 (n = 410)
Mushroom (width > 0.6 µm) 300 (75%) 190 (59.38%) 220 (73.33%) 245 (74.24%) 315 (76.83%)
Filopodia (length > 2 µm) 10 (2.5%) 5 (1.56) 30 (10.0%) 30 (9.09%) 35 (8.54%)
Stubby (LWR < 1 µm) 5 (1.25%) 0 (0%) 4 (1.33%) 5 (1.52%) 5 (1.22%)
Long thin (length < 1 µm) 10 (2.5%) 10 (3.12%) 5 (1.67%) 5 (1.52%) 5 (1.22%)
Thin (length < 2 µm) 50 (12.5%) 60 (18.72%) 5 (1.67%) 5 (1.52%) 5 (1.22%)
Branches (2 or more) 5 (1.25%) 55 (17.16%) 36 (12.0%) 40 (12.12%) 45 (10.98%)