Fig. 5. ML NK cells are transcriptionally distinct from cNK cells.
(A to C) Select differentially expressed genes conserved across both patients in ML NK cells (indicated within the gate) compared to all other clusters were visualized on TML-02 UMAP. Expression of activation, effector function, and NK receptors (A); adhesion and co-receptors (B); and transcription factors (C) are shown. Data were analyzed using a Wilcoxon rank sum test. n = 2 independent experiments. Cells are ordered on UMAPs according to normalized binned expression; see figs. S10 and S11. Adjusted P value or q value of <0.05 for all.