Table 1.

Summary of the alert symptoms for metastatic roots or spinal cord compression (MSCC) and progression of metastatic spine disease.

- neck or back nocturnal pain - axial mechanical pain (induced or worsened by movements and under pressure relieved by lying down) - sudden onset of axial pain - radicular pain radiating to arms or legs associated or not with numbness, tingling, dysesthesia - walking or balance difficulties or arms/hands weakness for impairment of one or more muscles - bladder or bowel control disorders, urinary retention