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. 2022 Jun 21;20:291. doi: 10.1186/s12951-022-01504-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — iPSCs-KCs-Exos promote the migration of keratinocytes and endothelial cells in vitro. A Representative fluorescence images of EdU staining of HaCaT cells treated with PBS or iPSCs-KCs-Exos (0.5, 1, 2, or 4 μg/mL) and quantitative analysis of the proliferation rates in each group. Scale bar, 200 μm. B Representative fluorescence images of EdU staining of HUVECs and quantitative analysis of the proliferation rates in each group. Scale bar, 200 μm. C Representative images of the wound healing assay and quantitative analysis of the wound healing rates in each group at 24 h. Scale bar, 200 μm. D Images of migrated HUVECs and quantitative analysis of the migrated cells in each group. Scale bar, 200 μm. *P < 0.05, **P < 0.01