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. 2022 Jun 7;12:922418. doi: 10.3389/fonc.2022.922418

Table 2.

Categorical comparison of cachexia incidence in prior medication use cohorts and patients without prior anti-inflammatory medication use.

Prior medication use (n) Patients with cachexia at diagnosis P-value
Total cohort (3180) 1083 (34.06%)
No anti-inflammatory medication (2521) 911 (36.14%)
Medication groups
 Any glucocorticoid (319) 90 (28.21%) 0.0053
 Any NSAID (479) 124 (25.89%) <0.0001
 Low-dose aspirin (301) 77 (25.58%) 0.0003
 Other nonselective NSAIDs (157) 42 (26.75%) 0.0172
 Selective COX-2 inhibitors (125) 34 (27.20%) 0.0418
 Metformin only (95) 31 (32.63%) 0.4685

P values bolded if <0.05.