Table 2.
Categorical comparison of cachexia incidence in prior medication use cohorts and patients without prior anti-inflammatory medication use.
Prior medication use (n) | Patients with cachexia at diagnosis | P-value |
---|---|---|
Total cohort (3180) | 1083 (34.06%) | |
No anti-inflammatory medication (2521) | 911 (36.14%) | |
Medication groups | ||
Any glucocorticoid (319) | 90 (28.21%) | 0.0053 |
Any NSAID (479) | 124 (25.89%) | <0.0001 |
Low-dose aspirin (301) | 77 (25.58%) | 0.0003 |
Other nonselective NSAIDs (157) | 42 (26.75%) | 0.0172 |
Selective COX-2 inhibitors (125) | 34 (27.20%) | 0.0418 |
Metformin only (95) | 31 (32.63%) | 0.4685 |
P values bolded if <0.05.