Table 2.
Genes involved in PIWIL biogenesis. FDR; false discovery rate, RPKM; median expression values expressed in reads per kilobase per million [15, 23, 24]
| Gene | HIR/LIR (RPKM) | log2FC / FDR | −/+ GnRHa treatment (RPKM) | log2FC / FDR |
|---|---|---|---|---|
| FOXA1 | 0.11/0.47 | −1.59/0.006 | 0.19/0.71 | 1.15/0.03 |
| ASZ1 | 0.75/309 | −2.32/0.001 | n.s. | n.s. |
| HSP90AA1 | 71.2/102.3 | −0.53/0.01 | 75.6/78.1 | −0.65/0.01 |
| HENMT1 | 7.52/20.11 | −1.34/0.0001 | 9.69/10.5 | −0.7/0.004 |
| FKBP6 | 0.47/2.16 | −2.34/0.0001 | 0.68/1.42 | n.s. |
| PIWIL1 | 0.39/2.21 | −2.97/0.0001 | n.s. | n.s. |
| PIWIL2 | 3.22/16.66 | −1.75/0.0008 | n.s. | n.s. |
| PIWIL3 | 0.22/0.41 | −1.0/0.015 | 0.17/0.95 | 1.52/0.002 |
| PIWIL4 | 1.72/7.32 | −2.09/0.0001 | n.s. | n.s. |
| PNLDC1 | 0.52/3.05 | −2.41/0.0006 | n.s. | n.s. |