| Methods |
Randomized single center trial
Blinding of randomization: yes
Blinding of intervention: can't tell
Complete follow‐up: yes
Blinding of outcome measurement: can't tell |
| Participants |
Birth weight less than 1500 grams
Assisted ventilation
Supplemental oxygen greater than 40%
Respiratory distress syndrome
Age less than 24 hours
Colfosceril palmitate (Exosurf Neonatal) n=33
Beractant (Survanta) n=33 |
| Interventions |
Beractant (Survanta) vs. colfosceril palmitate (Exosurf Neonatal)
Multiple doses |
| Outcomes |
Clinical Improvement
Days on assisted ventilation
Days on supplemental oxygen
Days in hospital
Mortality |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Low risk |
Blinding of randomization: yes |
| Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
Blinding of intervention: can't tell |
| Blinding of outcome assessment (detection bias)
All outcomes |
Unclear risk |
Blinding of outcome measurement: can't tell |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
Complete follow‐up: yes |
| Selective reporting (reporting bias) |
Low risk |
|
