Giannakopoulou 2002.

Methods	Unclear patient selection. Described as "randomly sampled from register numbers"
Participants	The study subjects were 92 premature newborns who had been hospitalized in the Department of Neonatology, of the University of Crete A total of 42 subjects received synthetic surfactant and 50 subjects received animal derived surfactant
Interventions	The surfactant was administered in one to three doses, depending on respiratory support requirements
Outcomes	The time of administration was a little longer for the animal derived surfactant group. The duration of mechanical ventilatory support, requiring oxygen, the duration of hospitalization and the percentage of increase of arterial alveolar partial pressure oxygen ratio (a/APO2) were slightly higher for the synthetic surfactant group The mortality rate during the neonatal period (28th day) was higher for the synthetic surfactant group than for the animal derived surfactant group (38.1 vs. 24%). A similar tendency was noticed also as regards to complications, e.g. pneumothorax (11.2 vs. 5.2%; relative risk (RR) 0.27) intraventricular hemorrhage (34.6 vs. 21.1%; RR 0.61), septicemia (11.5 vs. 5.2%; RR 0.46) and bronchopulmonary dysplasia (12.5 vs. 2.8%; RR 0.22)
Notes	Plan to contact authors re method of treatment assignment