Table 2.
Blood flow profile of rats with acute aflatoxicosis and after therapy.
| Parameters | Healthy control (n=8) | AFB1 (n=8) | AFB1+IV BM-MSCs (n=8) | AFB1+IH BM-MSCs (n=8) | AFB1+IV HDCs (n=8) | AFB1+IH HDCs (n=8) | p-value |
|---|---|---|---|---|---|---|---|
| PSV (cm/s) | 25.72±1.18 | 58.36*±6.41 | 38.41a±2.48 | 32.85a±3.76 | 49.61±3.29 | 29.95a±2.81 | 0.0032 |
| EDV (cm/s) | 9.18±2.03 | 2.01*±0.42 | 8.52a±1.93 | 9.78a±2.46 | 3.93±1.05 | 8.96a±1.77 | 0.0014 |
| TAMV (cm/s) | 8.05±0.64 | 14.25*±1.51 | 7.08a±1.28 | 8.42a±1.13 | 15.42±3.07 | 8.93a±0.72 | 0.0011 |
| Mean V (cm/s) | 15.62±1.28 | 19.04±3.38 | 14.90±2.18 | 16.48±2.38 | 18.76±3.58 | 15.33±1.49 | 0.0913 |
| S/D | 2.74±0.71 | 0.31*±0.07 | 1.23a±0.25 | 3.51a±1.02 | 0.66±0.13 | 0.43a±0.05 | 0.0011 |
| RI | 1.83±0.27 | 0.61*±0.13 | 1.53a±0.22 | 1.84a±0.33 | 0.76±0.19 | 1.87a±0.39 | 0.0013 |
| PI | 1.02±0.16 | 2.92*±0.53 | 1.78±0.37 | 1.46±0.18 | 2.79±0.52 | 1.88±0.33 | 0.0422 |
| G Mean (mmHg) | 0.12±0.03 | 0.29*±0.04 | 0.17±0.03 | 0.24±0.05 | 0.25±0.05 | 0.19±0.02 | 0.0321 |
| G Peak (mmHg) | 0.25±0.07 | 0.73*±0.15 | 0.39±0.04 | 0.33±0.08 | 0.63±0.14 | 0.26a±0.02 | 0.0824 |
• In the same row significantly different than control at P<0.01. and
a
is significantly different than AFB1 at P<0.01. AFB1=Aflatoxin B1, IV=Intravenous, IH=Intrahepatic, BM-MSCs=Bone marrow mesenchymal stem cells, HDCs=Hepatogenic differentiated cells, PSV=Peak systolic velocity, EDV=End diastolic velocity, TAMV=Time average maximum velocity, V=Mean velocity, S/D=Systolic/diastolic flow, RI=Resistance index, PI=Pulsatility index