Table 2.
Evaluation of the of the different prepared rabies vaccine formulae in the buccal cavity of dogs.
Used vaccine dose | Number of vaccinated dogs | SNT* titer | SNT mean | ELISA PI%** | ELISA PI% mean | Protection percentage |
---|---|---|---|---|---|---|
With stabilizer | 5 | 32 | Mean=28.8 | 71.3 | Mean=67.2 | 100% |
32 | 69.4 | |||||
32 | 65.8 | |||||
16 | 62.1 | |||||
32 | 67.4 | |||||
Adjuvated with 0.2% Carbopol | 5 | 16 | Mean=28.8 | 64.4 | Mean=65.88 | 100% |
32 | 73.1 | |||||
32 | 68.3 | |||||
16 | 63.1 | |||||
16 | 60.5 | |||||
Gel with 1% Carbopol | 5 | 8 | Mean=4.4 | 42.4 | Mean=33.84 | 0% |
4 | 38.2 | |||||
2 | 24.7 | |||||
4 | 34.2 | |||||
4 | 29.7 | |||||
Gel with SCMC | 5 | 32 | Mean=32 | 73.4 | Mean=68.84 | 100% |
64 | 76.7 | |||||
32 | 65.8 | |||||
16 | 64.9 | |||||
16 | 63.4 |
Mean SNT = the reciprocal of the final serum dilution which neutralized and inhibited the CPE of 100 TCID50 of rabies virus. (The protective SNT titer should not be less than 16).
ELISA PI% is ˃60% equivalent to 0.5IU/ML