Table 2.

Study participants by pubertal status and glucose tolerance at baseline

	BMI z	AUC insulin	Fasting insulin	Peak insulin	Insulin sensitivity	Insulinogenic index	ΔBMI z score
Pubertal status
Prepubertal (n = 128)	2.54 ± 0.36	184 ± 139	29 ± 18	326 ± 226	1.94 ± 1.11	4.32 ± 3.22	−0.09 ± 0.31
Pubertal (n = 463)	2.37 ± 0.31	205 ± 161	39 ± 22	341 ± 261	1.55 ± 0.88	5.36 ± 5.54	−0.04 ± 0.26
P value (t test)	<0.001	0.14	<0.001	0.52	0.001	0.01	0.17
Glucose tolerance
Normal (n = 407)	2.40 ± 0.32	170 ± 119	34 ± 20	302 ± 201	1.85 ± 1.00	5.53 ± 5.72	−0.03 ± 0.25
Impaired (n = 184)	2.42 ± 0.34	268 ± 202	43 ± 23	415 ± 330	1.16 ± 0.60	4.11 ± 3.22	−0.10 ± 0.30
P value (t test)	0.66	<0.001	<0.001	<0.001	<0.001	<0.001	0.01

Data are presented as means ± SD.

Fasting insulin and peak insulin expressed in microunits per milliliter; AUC insulin expressed in microunits per milliliter per minute; insulin sensitivity (Matsuda index) expressed as units; and insulinogenic index expressed in microunits per milliliter/micrograms per deciliter. Boldface P values indicate statistical significance.