FIGURE 1.

Advanced Blast Simulator and behavioral testing paradigms. A single shock wave (∼15 psi) was delivered with the mouse in an upright position with the ventral surface of the mouse exposed to the oncoming shock wave (see Vu et al., 2018 for a detailed description of the ABS). Eight days post-injury, animals underwent either EPM or EZM testing followed by the SPT 2 weeks post-injury or sham treatment, and lastly either TST or FST 3.5 weeks following ABS. Images reproduced from Abelaira et al. (2013), with permission from the Brazilian Journal of Psychiatry. Images reproduced from Brigman et al. (2010), Tucker and McCabe (2017).