TABLE 5.

Information about clusters with detectable sequence similarities to known Pfam adhesive domains

Cluster no.	Avg. scorea	Cluster size (no. of sequences)	Domain overlapb	UniProtKBc	UniProt Reference Proteomesc	MGnifyc
2	0.93 ± 0.06	8	Big_8 (PF17961), Collagen_bind (PF05737)	487d	19d	650d
6	0.86 ± 0.05	6	Collagen_bind (PF05737)	276d	66d	1,174d
8	0.84 ± 0.09	28	TED (PF08341)	1,149	222	48,395
15	0.78 ± 0.11	8	LRR_4 (PF12799)	45,022	2,793	170,274
17	0.78 ± 0.05	47	TED (PF08341)	1,170	170	54,096
19	0.77 ± 0.07	39	TED (PF08341)	954	148	28,283
21	0.74 ± 0.03	7	TED (PF08341)	56e	16e	3,617e
24	0.71 ± 0.05	13	TED (PF08341)	1,223	214	53,312

^aData shown are the average protein prediction score per cluster.

^bSimilar Pfam adhesive domains found with Jackhmmer are indicated.

^cThe numbers of homologous sequence hits per cluster in the UniProtKB, UniProt Reference Proteomes, and MGnify databases are shown.

^dC-terminal domain.

^eN-terminal domain.