Table 1.
Comparisons between the effects obtained in adult (Awad et al., 2015) and juvenile animals (present study)a
| Treatment | Juveniles (present results) | Adults (Awad et al., 2015) | |||
|---|---|---|---|---|---|
| Age at training | PND 27 | ~PND 60 | |||
| Age at test | PND 28-30 (recent) | ~PND 60 (remote) | ~PND 60 (recent) | ~PND 90 (remote) | |
| Lidocaine in IL-mPFC before T1 | COA retrieval | 0 | 0 | ä | ä |
| CFC retrieval | 0 | æ | – | – | |
| Anisomycin in IL-mPFC after T1 | COA extinction consolidation | 0 | 0 | æ | 0 |
| CFC extinction consolidation | æ | 0 | æ | æ | |
Abbreviations: 0, no effect; æ, impairment; ä, enhancement; –, not determined.
a Note that remote memory in post-weanlings-trained rats was evaluated at the same age as recent memory in adult-trained rats (approximately postnatal day 60).