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. 2022 Jun 7;13:898062. doi: 10.3389/fphar.2022.898062

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Copyright © 2022 Khan, Iqtadar, Mumtaz, Heinrich, Pascual-Figal, Livingstone and Abaidullah.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Scatter plots of individual patients’ day seven biomarker values against their corresponding baseline values in the two treatment arms, CQC (blue) and control (pink): (A) CRP, (B) D-dimer, (C) LDH, and (D) ferritin. Scatter plots overlaid with smoothed LOESS curves to help visualize any patterns. Diagonal dashed line denotes line of equality while horizontal dashed line represents the biomarker upper normal limit. The shading represents uncertainty around the smoothed lines between the points.