TABLE 1.
Known SLID-R markers in M. tuberculosisa
Antibiotic | Known markers |
---|---|
AMK | rrs:A1401G, rrs:G1484T, eis:C-14T |
CAP | rrs:A1401G, rrs:G1484T |
KAN | rrs:A1401G, rrs:G1484T, eis:G-10A, eis:C-12T, eis:C-14T |
This set of mutations was derived from the WHO-endorsed catalogue of resistance-associated mutations (18) and used to determine the expected resistance of clinical isolates to AMK, CAP, and KAN.