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Efficacy of GSK2556286 (G) combined with the various 2- and 3-drug combinations of B (bedaquiline), Pa (pretomanid), and L (linezolid) for 1 month (A) or 2 months (B) in a C3HeB/FeJ mouse model of TB. For comparison, B, BG, and BPaL are included. Bars indicate median CFU counts. The median CFU on day 0, the start of treatment, is indicated by the dotted line.
