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Efficacy of GSK2556286 combined with B and Pa in a BALB/c mouse model of TBa
| Regimen | Mean lung log10 CFU ± SD |
||
|---|---|---|---|
| Day 0 | Mo 1 | Mo 2 | |
| Untreated | 7.87 ± 0.12 | ||
| BPa | 5.54 ± 0.32 | 3.17 ± 0.20 | |
| BPaL | 4.73 ± 0.28 | 0.73 ± 0.52 | |
| BPa+GSK2556286 | 5.39 ± 0.18 | 1.74 ± 0.76 | |
For comparison, the three-drug combination BPaL is included.
