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Structures and antimalarial data for compounds demonstrating sub μM activity in the PfIVT assay
| Compound (reference) | Structure | P. falciparum asexual-blood-stage EC50 (μM) | PfIVT IC50 (μM) |
|---|---|---|---|
| MMV019189 (35) |
|
0.75a | 0.03 ± 0.009 |
| MMV1578897 (30) |
|
5b | 0.04 ± 0.008 |
| MMV687807 (29) |
|
1.8a | 0.09 ± 0.007 |
| MMV667494 (44) |
|
0.010a | 0.3 ± 0.09 |
| MMV676008 (48) |
|
>20a | 0.4 ± 0.08 |
| MMV688372 (31) |
|
13.6 | 0.6 ± 0.06 |
| MMV634140 (12) |
|
0.09a | 3 ± 0.09 |
| MMV1580839 (34) |
|
5b | 0.8 ± 0.08 |
