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Dosing recommendations for susceptible isolates
| CLCR (mL/min) | Dosing recommendationa |
|---|---|
| ≤60 | 1 g twice daily |
| 61–139 | 1 g 3 times daily |
| ≥140 | 1 g LD then 2–4 g CI or 2 g twice daily |
Assuming a MIC of 1 mg/L and a PTA of ≥90%. Lower doses may be suitable for isolates with a MIC of <1 mg/L, depending on the patient’s clinical context.
