Table 1.
Baseline Characteristics of the Patients by Treatment Groups in Study 1
| Olanzapine plus probiotics | Olanzapine alone | ||||
|---|---|---|---|---|---|
| (N = 39) | (N = 37) | ||||
| Mean | SD | Mean | SD | Normal range | |
| Age, y | 24.82 | 5.64 | 23.43 | 4.89 | |
| Duration of illness, mo | 11.49 | 3.51 | 11.08 | 3.64 | |
| Dose of olanzapine, mg | 19.36 | 1.59 | 18.85 | 1.92 | |
| Weight, kg | 55.63 | 7.54 | 56.75 | 8.35 | |
| Body mass index, kg/m2 | 21.26 | 2.59 | 21.25 | 1.69 | 18.5–23.9 kg/m2 |
| Fasting glucose, mmol/L | 4.41 | 0.39 | 4.40 | 0.37 | 3.90–6.10 mmol/L |
| Fasting insulin, µIU/mL | 8.07 | 2.88 | 7.85 | 1.72 | 6.40–15.0 uIU/mL |
| IRI | 1.59 | 0.59 | 1.54 | 0.38 | <2.67 |
| Triglyceride, mmol/L | 0.86 | 0.41 | 0.72 | 0.26 | <1.71 mmol/L |
| Cholesterol, mmol/L | 3.75 | 0.58 | 3.70 | 0.48 | 2.90–5.20 mmol/L |
| HDL-C, mmol/L | 1.21 | 0.18 | 1.23 | 0.14 | >1.04 mmol/L |
| LDL-C, mmol/L** | 2.39 | 0.44 | 2.10 | 0.36 | <3.12 mmol/L |
| Total score of PANSS | 79.77 | 5.37 | 79.65 | 7.37 | |
| N | % | N | % | ||
| Female | 11 | 28 | 13 | 35 | |
| Male | 28 | 72 | 24 | 65 | |
Med, median; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.
** p < .01, compared between the two treatment groups.