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. 2022 Apr 14;48(4):839–849. doi: 10.1093/schbul/sbac035

Table 2.

Clinical Recovery Rates in Healthy Controls and Total Sample, and Between Schizophrenia and Bipolar Spectrum Groups at 10-year Follow-up

Healthy Controls
(n = 117)
Total Sample (n = 142) Chi-square/t-test/Mann Whitney Schizophrenia
Spectrum
(n = 96)
Bipolar
Spectrum
(n = 46)
Chi-square/t-test/Mann Whitney
χ2/t/U p V/D χ2/t/U p V/D
Standard Clinical Recovery Criteria
Clinical Recovery a 45 (31.7) 22 (22.9) 23 (50.0) χ2 = 10.54 .002 .272
 Psychotic Remissionb 85 (59.9) 44 (51.8) 41 (89.1) χ2 = 24.26 .000 .413
 Adequate Functioningc 95 (81.2) 46 (32.4) χ2 = 61.60 .000 .488 23 (24.0) 23 (50.0) χ2 = 9.63 .004 .260
 Independent Living 117 (100.0) 111 (78.2) χ2 = 29.02 .000 .335 69 (71.9) 42 (91.3) χ2 = 6.88 .009 .220
 Social Functioning 101 (86.3) 79 (55.6) χ2 = 28.10 .000 .330 49 (51.0) 30 (65.2) χ2 = 2.53 .149 .134
 Full-time Occupationd (work/study/other) 111 (94.9) 48 (33.8) χ2 = 100.93 .000 .624 25 (26.0) 23 (50.0) χ2 = 7.98 .008 .237
Altering Clinical Recovery Criteria
Duration
 Duratione, Present/No Duration 52 (36.6) 25 (26.0) 27 (58.7) χ2 = 14.29 .000 .317
 Duratione, 6 months 50 (35.2) 24 (25.0) 26 (56.5) χ2 = 13.55 .000 .309
 Duratione, 24 months 38 (26.8) 18 (18.8) 20 (43.5) χ2 = 9.70 .003 .261
 Duratione, 60 months 25 (17.6) 13 (13.5) 12 (26.1) χ2 = 3.37 .098 .154
Symptom Remission
 Psychotic + Affective Remissionf 38 (26.8) 17 (17.9) 21 (45.7) χ2 = 12.13 .001 .293
  Affective Remissiong 83 (58.5) 56 (58.9) 27 (58.7) χ2 = 0.00 1.000 .002
Adequate Functioning
Social functioning—Close friendh 110 (94.0) 46 (32.4) χ2 = 101.70 .000 .627 23 (24.0) 23 (50.0) χ2 = 9.63 .004 .260
Part-time Occupationi 97 (82.9) 52 (36.6) χ2 = 57.81 .000 .473 25 (26.0) 27 (58.7) χ2 = 14.29 .000 .317
Part-time Occupation + Close friendj 112 (95.7) 58 (40.8) χ2 = 85.66 .000 .575 27(28.1) 31 (67.4) χ2 = 19.85 .000 .374
Partial function + Affective Remission k 45 (31.7) 21 (21.9) 24 (52.2) χ2 = 13.19 .000 .305

Note: N (%) is reported for all. Missing: Social Functioning total sample = 1; Affective remission = 1.

a Standard clinical recovery definition: Psychotic symptom remission and adequate functioning, 12 months duration

b RGSW consensus criteria (Andreasen et al., 2005): 12 months duration.

c Adequate functioning: 12 months duration.

d Occupation: work/study/other.

e Duration: required period of psychotic remission and adequate functioning (original criteria)

f Standard recovery criteria with adding affective remission (IDS-C (Inventory of Depressive Symptoms-Clinician Rated) < 14/CDSS < 7/YMRS < 8, no current episode).

g Affective remission (IDS-C (Inventory of Depressive Symptoms-Clinician Rated) < 14/CDSS < 7/YMRS < 8, no current episode) with 12 months duration.

h Standard recovery criteria with altered social functioning criteria to having a close friend/confidant from meeting friend once weekly. For controls, functioning criteria only.

i Standard recovery criteria with altered occupation to part-time instead of full-time.

j Including both part-time occupation and Social functioning-close friend/confidant (h and i).

k Standard recovery criteria and adding both Part-time occupation + Social functioning-close friend (partial function) and affective symptom remission.