Table 1.
Baseline Sample Characteristics of the Various Demographics, Clinical Variables, and Primary, Secondary Outcome Measures
Variables | Groups | P Value | |
---|---|---|---|
Group-1 (M-ECT) (n = 30) | Group-2 (Clozapine) (n = 30) | ||
Male:female (%) | 60:40 | 57:43 | .99 |
Age (in years) | 34.47 ± 10.29 | 35.80 ± 10.36 | .62 |
Education (in years) | 11.77 ± 3.75 | 12.23 ± 3.48 | .62 |
Age of onset (in years) | 25.5 ± 9.58 | 22.67 ± 5.76 | .17 |
Duration of illness (DOI) (in years) | 9.6 ± 7.36 | 12.8 ± 7.98 | .11 |
PANSS-P | 35.65 ± 4.87 | 35.78 ± 5.20 | .93 |
PANSS-N | 36.96 ± 6.35 | 37.41 ± 6.63 | .79 |
PANSS-G | 70.69 ± 9.69 | 70.85 ± 10.02 | .95 |
PANSS-T | 143.31 ± 14.13 | 144.04 ± 17.85 | .86 |
CGI-SCH-S | 6.192 ± 0.49 | 6.185 ± 0.60 | .96 |
MOCA | 19.08 ± 2.36 | 19.22 ± 2.19 | .81 |
GAF | 24.85 ± 5.97 | 22.11 ± 8.22 | .15 |
Regional cerebral blood perfusion (SPECT-CT brain)a | |||
RLPFC | −0.108 ± 0.04 | −0.118 ± 0.06 | .47 |
LLPFC | −0.103 ± 0.05 | −0.110 ± 0.06 | .62 |
RMPFC | −0.053 ± 0.06 | −0.06 ± 0.06 | .47 |
LMPFC | −0.057 ± 0.06 | −0.088 ± 0.15 | .30 |
RLT | −0.062 ± 0.04 | −0.047 ± 0.05 | .22 |
LLT | −0.061 ± 0.05 | −0.046 ± 0.06 | .28 |
RMT | −0.030 ± 0.05 | −0.022 ± 0.06 | .52 |
LMT | −0.018 ± 0.04 | −0.001 ± 0.05 | .14 |
RSP | −0.019 ± 0.05 | −0.020 ± 0.05 | .92 |
LSP | −0.002 ± 0.05 | −0.021 ± 0.05 | .16 |
RIP | −0.064 ± 0.03 | −0.067 ± 0.06 | .80 |
LIP | −0.062 ± 0.05 | −0.076 ± 0.06 | .28 |
Data are in mean ± SD, Independent t-test/Fisher’s exact test.
aValues of SPECT-CT brain reflect the difference of regional cerebral blood perfusion of patient from normal reference. RLPFC, right lateral prefrontal cortex; LLPFC, left lateral prefrontal cortex; RMPFC, right medial prefrontal cortex; LMPFC, left media prefrontal cortex; RLT, right lateral temporal; LLT, left lateral temporal; RMT, right medial temporal; LMT, left medial Temporal; RSP, right superior parietal; LSP, left superior parietal; RIP, right inferior parietal; LIP, left inferior parietal.