Table 1.
Demographic and Clinical Characteristics of Healthy Controls Versus Total Patient Population, and NEET Patients Versus EET Patients
| Variable | Healthy Control n = 30 | All Patients n = 57 |
HC vs Patient | EET Patient n = 31 | NEET Patient n = 26 | EET vs NEET |
|---|---|---|---|---|---|---|
| Demographic Data | ||||||
| Sex(Male/Female) | 19/11 | 48/9 | x2 = 4.83, P = .028 | 25/6 | 23/3 | x2 = 0.65, P = .42 |
| Age [M (SD)} | 21.57 (3.45) | 22.75 (4.28) | t(85) = 1.5, P = .14 | 22.16 (3.92) | 23.46 (5.29) | t(55) = –1.10, P = .274 |
| ParentalNS-SEC[M (SD)} | 3.20(1.42) | 3.34 (1.27) | t(80) = 0.47, P = .64 | 3.31 (1.11) | 3.42 (1.38) | t(51) = 0.47, P = .64 |
| Avg Months to NEET assessment | N/A | 9.00 (4.38) | N/A | 8.90 (3.96) | 10.04 (4.79) | t(55) = 1.79, P = .08 |
| CAST Score | 6.13 (0.73) | 12.38 (5.94) | t(75) = –5.72, P < .01 | 12.00 (5.88) | 12.76(6.09) | t(45) = 0.49, P = .625 |
| AUDIT-C | 2.77 (2.10) |
2.25 (2.63) |
t(79) = 0.91 P = .37 |
2.79 (2.69) | 1.61 (2.46) | t(49) = 1.61, p=0.12 |
| Smoker (Yes/ No) | 0/30 | 11/46 | x2 = 6.62, P = .01 | 5/26 | 6/20 | x2 = 0.44, P = .51 |
| Clinical Data | ||||||
| DUP [M (SD)] | N/A | 5.63 (5.74) | N/A | 5.60 (5.80) | 5.67 (5.82) | t(53) = –0.04, P = .97 |
| Antipsychotic Defined Daily Dose Equivalents | N/A | 1.80 (2.81) | N/A | 1.62 (3.03) | 1.79 (2.09) | t(55) = –0.06, P = .96 |
| Other Psychotropic Medication (yes/ no) | N/A | 13/57 | N/A | 9/31 | 4/26 | x2 = 1.42, P = .22 |
| Baseline SOFAS [M (SD)] | 82.92(4.20) | 41.04 (12.48) | t(77) = 16.30, P < .001 | 44.38 (14.31) | 37.00 (8.45) | t(52) = 2.22, P = .03 |
| Follow-up SOFAS [M (SD)] | N/A | 59.34 (13.70) | N/A | 67.68 (10.08) | 48.37 (9.44) | t(42) = 6.47, P < .001 |
| PANSS-8 Total [M (SD)] | 8.0 (0.00) | 24.98 (5.76) | t(82) = 13.8, P < .01 | 24.07(4.95) | 26.13 (6.57) | t(52) = –0.83, P = .41 |
| PANSS-8 Positive [M (SD)} | 3.0 (0.00) | 12.35 (2.32) | t(82) = 18.6, P < .01 | 12.03 (2.44) | 12.75 (2.15) | t(52) = –0.94, P = .35 |
| PANSS-8 Negative [M (SD)} | 3.0 (0.00) | 7.22 (4.17) | t(82) = 5.67, P < .01 | 6.63 (3.76) | 7.96 (4.61) | t(52) = –0.86, P = .39 |
| CGI- Severity | 1.00 | 5.19 (0.97) | t(81) = 23.15, P < .01 | 5.10 (1.13) | 5.29 (0.75) | t(52) = –0.85, P = .40 |
M, Mean; SD, standard deviation; NS-SEC, national statistics socio-economic classification; CAST, Cannabis Abuse Screening Test; DUP, Duration of untreated Psychosis in Months; NEET, Not engaged in employment education or training; EET, Engaged in employment education or training; SOFAS, Social and Occupational Functioning Assessment Score; PANSS-8, Positive and Negative Syndrome Scale—8 Item Scale; PANSS-8 Positive, Positive and Negative Syndrome Scale total score for positive symptom items; PANSS-8 Negative, Positive and Negative Syndrome Scale total score for negative symptom items; CGI-Severity, Clinical Global Impression—Severity.