Fig 6. Receiver operating characteristic curves and their corresponding areas under the curve from the best performing IgG responses in detecting current Plasmodium falciparum infection.

A. IgG responses (log₁₀-transformed median fluorescence intensity [MFI] levels) against LSA1, EXP1, AMA1, EBA175, MSP1₄₂, MSP2, MSP3, MSP5, Rh1 and PTRAMP in serum samples from 715 endemic individuals and 50 Spanish donors were used as predictor variables and qPCR results as response variable. B. IgG responses (log₁₀-transformed MFI levels) against EXP1, AMA1 and MSP2 in serum samples from children (N = 363) and adults (N = 352) were used as predictor variables and qPCR results were used as response variable. In each age group, antibody levels in samples from the 50 Spanish donors were used as negative controls. AUC: Area Under the Curve.