Table 2. Results of the primary analysis.
| Cost component | Per annual caseload (EUR)a | Per procedure (EUR) | ||||
|---|---|---|---|---|---|---|
| HARMONIC FOCUS™+ | Monopolar electrocautery | Cost differenceb | HARMONIC FOCUS™+ | Monopolar electrocautery | Cost differenceb | |
| Device costs | 55,167 | 11,899 | 43,268 | 552 | 119 | -433 |
| OR time costs | 80,823 | 84,337 | -3,514 | 808 | 843 | -35 |
| Hospital stay costs | 196,580 | 327,633 | -131,053 | 1,966 | 3,276 | -1,311c |
| Complication costsd | 12,854 | 21,598 | -8,744 | 129 | 216 | -87 |
| Overall costs | 345,424 | 445,467 | -100,043 | 3,455 | 4,455 | -1,000 |
aAssumes an annual caseload of 100 procedures (mastectomy with ALND or BCS with ALND)
bcost difference calculated as the component value of the intervention minus component value for comparator such that negative values indicate cost saving with the intervention
cdiscrepancy with the difference between intervention and comparator per procedure costs is due to rounding
dcomprises costs for management and treatment of seroma and postoperative chest wall drainage.
Abbreviations: ALND: axillary lymph node dissection; BCS: breast-conserving surgery; EUR: Euros; OR: operating room.