Table 1.
Demographic and laboratory data (n = 78).
| Variables | Control (n = 20) |
Mild (n = 17) |
Moderate (n = 18) |
Severe (n = 23) |
p | η2⁎⁎⁎ |
|---|---|---|---|---|---|---|
| Age (years) | 41.7 ± 12.72 | 34.59 ± 8.94 | 39.94 ± 9.88 | 45.39 ± 7.47 | 0.003⁎⁎ | 0.139 |
| Gender (female) | 10(50) | 9(52.9) | 8(44.4) | 13(56.5) | 0.891 | |
| Body mass index (kg/m2) | 27.95 ± 4.52 | 26.07 ± 3.639 | 28.48 ± 5.63 | 30.64 ± 4.83 | 0.029⁎ | 0.114 |
| Comordities | ||||||
| Diabetes mellitus | 3(15) | 1(5.9) | 1(5.6) | 4(17.4) | 0.538 | – |
| Hypertension | 2(10) | 0(0) | 1(5.6) | 3(13) | 0.456 | – |
| Coronary artery disease | 1(50) | 0(0) | 0(0) | 1(50) | 0.639 | – |
| Others | 2(10) | 1(5.9) | 1(5.6) | 3(13) | 0.814 | – |
| Neurological symptoms | ||||||
| Headache | – | 10(58.8) | 17(94.4) | 20(87) | 0.018 | – |
| Ageusia | – | 11(64.7) | 13(72.2) | 18(78.3) | 0.638 | – |
| Anosmia | – | 11(64.7) | 11(61.1) | 14(60.9) | 0.965 | – |
| Vertigo | – | 1(5.9) | 5(27.8) | 6(26.1) | 0.199 | – |
| Peripheral neuropathy | – | 0(0) | 0(0) | 1(100) | 0.384 | – |
| Cranial nerve affection | – | 0(0) | 0(0) | 1(100) | 0.585 | – |
| Cognitive deficits | – | 0(0) | 0(0) | 1(100) | 0.338 | – |
| Biomarkers | ||||||
| GFAP (pg/mL) | 43.74 ± 23.40 | 63.72 ± 78.89 | 83.19 ± 57.70 | 86.43 ± 63.17 | 0.007⁎⁎ | 0.086 |
| S100B (pg/mL) | 21.26 ± 10.40 | 17.40 ± 13.82 | 16.97 ± 8.02 | 14.24 ± 7.18 | 0.158 | 0.067 |
Values are expressed as n(%) or mean ± SD. GFAP indicates glial fibrillary acidic protein.
⁎⁎
Bonferroni.
⁎
Tamhane's T.
⁎⁎⁎
: Partial Eta Squared.