Fig. 3.

Ribbon and surface diagrams showing the interface region of interaction between the spike RBD (tan) and the neutralising antibody with its heavy and light chain (violet) complex (for antibody CC12.1) for (A) Wild Type (B) Delta and (C) Omicron variant. Interacting residues of the spike RBD, the mutated residues and the antibody interacting residues are displayed in red, green and cyan colour respectively. RBD residues which are mutated and interact with antibodies are shown in blue. Interacting residues present in the vicinity (6 Å) of the mutated residues of the spike RBD are shown in orange.