Table I.
Characteristics of patients who were on low-molecular-weight heparin (LMWH) vs unfractionated heparin (UFH) prophylactic vs therapeutic level of AC
| LMWH | UFH | P value | |
|---|---|---|---|
| SOFA prophylactic (mean ± SD) | 5.8 ± 0.23 | 4.09 ± 0.95 | .04 |
| SOFA therapeutic (mean ± SD) | 5.8 ± 0.24 | 7.6 ± 0.25 | .5 |
| Max D-dimer for prophylactic (mean ± SE) | 3472 ± 458 | 3223 ± 989 | .64 |
| Max D-dimer for therapeutic (mean ± SE) | 12,672 ± 1618 | 11,743 ± 1470 | .67 |
| Admit creatinine for prophylactic (mean ± SE) | 0.99 ± 0.11 | 1.34 ± 0.25 | .14 |
| Admit creatinine for therapeutic (mean ± SE) | 0.98 ± 0.06 | 1.9 ± 0.25 | .001 |
| Max creatinine for prophylactic (mean ± SE) | 1.46 ± 0.18 | 3.18 ± 0.7 | .017 |
| Max creatinine for therapeutic (mean ± SE) | 1.37 ± 0.1 | 4.63 ± 0.34 | .001 |
| Max CRP, prophylactic (mean ± SE) | 36.18 ± 4.9 | 39.49 ± 13.7 | .97 |
| Max CRP, therapeutic (mean ± SE) | 40.4 ± 4.3 | 39.7 ± 3.8 | .88 |
| Max interleukin 6 (Vivacor), prophylactic (mean ± SE) | 218 ± 70 | 1949 ± 1134 | .003 |
| Max interleukin 6 (Vivacor), therapeutic (mean ± SE) | 428 ± 120 | 284 ± 73 | .6 |
AC, Anticoagulation; CRP, C-reactive protein; SD, standard deviation; SE, standard error; SOFA, Sequential Organ Failure Assessment.
Boldface P values represent statistical significance.