Table III.
Comparing the complications of low-molecular-weight heparin (LMWH) vs unfractionated heparin (UFH) in prophylactic vs therapeutic AC doses
| Complications | Prophylactic (UFH: 11, LMWH: 70) | Therapeutic (UFH: 72, LMWH: 65) | P value |
|---|---|---|---|
| Thromboembolic | |||
| UFH | 9% | 18.06% | .45 |
| LMWH | 4.2% | 13.8% | .051 |
| Bleeding | |||
| UFH | 18.1% | 31.9% | .35 |
| LMWH | 4.2% | 21.54% | .002 |
| HIT | |||
| UFH | 0 | 4.17% | |
| LMWH | 0 | 1.54% | |
| Received transfusion | |||
| UFH | 36.3% | 72.2% | .0008 |
| LMWH | 18.5% | 38.46% | .002 |
| Therapeutic UFH (n = 72) | Therapeutic LMWH (n = 65) | ||
|---|---|---|---|
| Thromboembolic | 18.06% | 13.8% | .5 |
| PE/DVT | 9.7% | 9.2% | .9 |
| Arterial complications | 9.7% | 9.2% | .9 |
| Bleeding | 31.9% | 21.54% | .17 |
| HIT | 4.17% | 1.54% | .36 |
| Received transfusion | 72.2% | 38.46% | .001 |
| Prophylactic UFH (n = 11) | Prophylactic LMWH (n = 70) | ||
|---|---|---|---|
| Thromboembolic | 9% | 4.2% | .49 |
| Bleeding | 18.1% | 4.2% | .075 |
| HIT | 0% | 0% | |
| Received transfusion | 36.3% | 18.5% | .17 |
AC, Anticoagulation; DVT, deep vein thrombosis; HIT, heparin-induced thrombocytopenia; PE, pulmonary embolism.
Boldface P values represent statistical significance.